Article
The estimation of GC repeats in promoter P1 of IGF-1 gene and their influence on IGF-1 plasma levels in stable angina patients.
The protein journal - 1 Oct 2010
Burchardt Pawel, Nowak Witold, Zurawski Jakub, Gozdzicka-Jozefiak Anna, Siminiak Tomasz
Abstract excerpt
UNLABELLED: Increased plasma levels of insulin-like growth factor 1 (IGF-1) are observed in advanced arteriosclerosis, but the reasons for these elevated levels remain unknown. One possibility to explain them is variation in the sequences that control IGF-1 gene expression. The goal of this study was to determine the effect of molecular variants of the IGF-1 P1 promoter on IGF-1 serum levels and to determine the...
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