Article
[Analysis of genotype combinations at the polymorphic points of the promoter regions of the genes of three matrix metalloproteinases and the gene of vascular endothelial growth factor (VEGF) in patients with history of acute myocardial infarction].
Terapevticheskii arkhiv - 1 Jan 2014
Shevchenko A V, Konenkov V I, Prokof'ev V F, Pokushalov E A
Abstract excerpt
AIM: To analyze the association of the promoter polymorphism of the genes of the matrix metalloproteinases (MMP) MMP2 (-1306), MMP3 (-1171), and MMP9 (-1562) and two vascular endothelial growth factor (VEGF) gene regulatory regions (-2578, +936) with the development of myocardial infarction (MI). MATERIALS AND METHODS: DNA was analyzed in 251 patients with a history of MI. Five polymorphic positions were...
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