Article
Presence of irregularity in region between -1115 and -784 nt in P1 promoter of insulin-like growth factor-1 gene may indicate beneficial effect on coronary arteries in a group of patients with stable angina: preliminary data.
Heart and vessels - 1 Jul 2009
Burchardt Pawel, Nowak Witold, Gozdzicka-Jozefiak Anna, Link Rafal, Grotowski Tomasz, Wisniecka Anna, Siminiak Tomasz
Abstract excerpt
Insulin-like growth factor-1 (IGF-1) plays an important role in arterial homeostasis. Its properties seem to depend on circulating IGF-1 level changes. The various IGF-1 levels are caused by varied expression of IGF-1 gene, due to the polymorphic structure of IGF-1 gene or its regulatory sequence...
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