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Article

The importance of the (TAAAA)n alleles at the SHBG gene promoter for the severity of coronary artery disease in postmenopausal women.

Menopause (New York, N.Y.) - 1 Jan 2000

Alevizaki Maria, Saltiki Katerina, Xita Nectaria, Cimponeriu Adriana, Stamatelopoulos Kimon, Mantzou Emily, Doukas Charalambos, Georgiou Ioannis

Abstract excerpt

OBJECTIVE: Androgen may be detrimental in the development of coronary artery disease (CAD) in women. We investigated possible associations between the (TAAAA)n polymorphism of sex hormone-binding globulin (SHBG) gene promoter, which influences transcriptional efficiency of the SHBG gene and the severity of CAD in women. DESIGN: In this prospective clinical study, 146 postmenopausal women (46-88 y) undergoing...

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Source

Identifiers

PMID: 18188141
DOI: 10.1097/gme.0b013e31814faf41

Genes

SHBG
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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