Article
[Phenotyping of apolipoprotein E: immunoblotting after isoelectric focusing in immobilized pH gradients].
Klinische Wochenschrift - 1 Jan 1990
März W, Cezanne S, Gross W
Abstract excerpt
Apolipoprotein E is a major ligand for cellular lipoprotein receptors and plays an important role in the catabolism of triglyceride-rich lipoproteins. The polymorphism of apo E is associated with familial dysbetalipoproteinemia, LDL-cholesterol, and cardiovascular risk. In this report a method for the analysis of apo E isoforms in immobilized pH gradients is presented that does not require isolation apo E...
Topics
- Apolipoproteins E
- Humans
- Hydrogen-Ion Concentration
- Immunoblotting
- Isoelectric Focusing
- Phenotype
- Polymorphism, Genetic
