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Article

Lower prevalence of common filaggrin mutations in a community sample of atopic eczema: is disease severity important?

Wiener klinische Wochenschrift - 1 Oct 2010

Gruber Robert, Janecke Andreas R, Grabher Daniela, Horak Elisabeth, Schmuth Matthias, Lercher Peter

Abstract excerpt

BACKGROUND: Recent studies have shown an association of loss-of-function mutations in the filaggrin gene (FLG) with ichthyosis vulgaris and atopic eczema (AE). Case selection may have distorted the hitherto reported prevalence of FLG mutations and their relation to atopic disease. The aim of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20865458
DOI: 10.1007/s00508-010-1449-3

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20865458-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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