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Article

Self-contained gene-set analysis of expression data: an evaluation of existing and novel methods.

PloS one - 17 Sept 2010

Fridley Brooke L, Jenkins Gregory D, Biernacka Joanna M

Abstract excerpt

Gene set methods aim to assess the overall evidence of association of a set of genes with a phenotype, such as disease or a quantitative trait. Multiple approaches for gene set analysis of expression data have been proposed. They can be divided into two types: competitive and self-contained. Benefits of self-contained methods include that they can be used for genome-wide, candidate gene, or pathway studies, and...

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Identifiers

PMID: 20862301
DOI: 10.1371/journal.pone.0012693
PMCID: PMC2941449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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