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Article

Identifying the genetic variation of gene expression using gene sets: application of novel gene Set eQTL approach to PharmGKB and KEGG.

PloS one - 1 Jan 2012

Abo Ryan, Jenkins Gregory D, Wang Liewei, Fridley Brooke L

Abstract excerpt

Genetic variation underlying the regulation of mRNA gene expression in humans may provide key insights into the molecular mechanisms of human traits and complex diseases. Current statistical methods to map genetic variation associated with mRNA gene expression have typically applied standard linkage and/or association methods; however, when genome-wide SNP and mRNA expression data are available performing all...

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Identifiers

PMID: 22905253
DOI: 10.1371/journal.pone.0043301
PMCID: PMC3419168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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