Article
Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations.
Computational biology and chemistry - 1 Jun 2007
Gusnanto Arief, Tom Brian, Burns Philippa, Macaulay Iain, Thijssen-Timmer Daphne C, Tijssen Marloes R, Langford Cordelia, Watkins Nicholas, Ouwehand Willem, Berzuini Carlo, Dudbridge Frank
Abstract excerpt
Our ability to detect differentially expressed genes in a microarray experiment can be hampered when the number of biological samples of interest is limited. In this situation, we propose the use of information from self-self hybridizations to acuminate our inference of differential expression. A...
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