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Article

IL-7Rα confers susceptibility to experimental autoimmune encephalomyelitis.

Genes and immunity - 1 Jan 2011

Walline C C, Kanakasabai S, Bright J J

Abstract excerpt

Multiple sclerosis (MS) is a neurological disorder that causes paralysis in young adults and affects women more frequently than men. The etiology of MS is not known, but it is generally viewed as an autoimmune disease of the central nervous system (CNS), influenced by genetic and environmental factors. Recent studies have identified interleukin-7 receptor α (IL-7Rα) as a risk factor for MS. But the role of IL-7Rα...

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Share to Autoantigens
Share to CD4-Positive T-Lymphocytes
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-4

Share to Myelin Sheath

Share to Receptors, Interleukin-7

Share to T-Lymphocytes, Regulatory

Source

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Identifiers

PMID: 20861865
DOI: 10.1038/gene.2010.49
PMCID: PMC3024464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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