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Interleukin-1, inflammasomes, autoinflammation and the skin

20 May 2012

Abstract excerpt

Interleukin 1, one of the first cytokines discovered in the 1980s, and a potent mediator of fever, pain and inflammation, is at present experiencing a revival in biology and medicine. Whereas the mechanism of activation and secretion of interleukin 1β, which critically regulates the function of this molecule, has remained mysterious for some 30 years following its discovery, the identification of a new...

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PMID: 22653747
DOI: 10.4414/smw.2012.13590

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