Article
Pharmacogenomics and antidepressant drugs.
Annals of medicine - 1 Jan 2006
Binder Elisabeth B, Holsboer Florian
Abstract excerpt
While antidepressant pharmacotherapy is an effective treatment of depression, it still is hampered by a delayed time of onset of clinical improvement and a series of side effects. Moreover, a substantial group of patients has only limited response or fails to respond at all. One source accounting for these variations are genetic differences as currently analysed by single nucleotide polymorphisms (SNP) mapping....
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