Article
T-helper 1, T-helper 2, and T-regulatory cytokines gene polymorphisms in irritable bowel syndrome.
Inflammation - 1 Oct 2010
Barkhordari Elham, Rezaei Nima, Mahmoudi Mahdi, Larki Pegah, Ahmadi-Ashtiani Hamid Reza, Ansaripour Bita, Alighardashi Maryam, Bashashati Mohammad, Amirzargar Ali Akbar, Ebrahimi-Daryani Naser
Abstract excerpt
Inflammation and mucosal immune system activation have an important role in irritable bowel syndrome (IBS), whereas genetic factors can control some immunological mediators. In this study, a number of polymorphic genes coding for T-helper 1, T-helper 2, and T-regulatory cytokines were genotyped in 71 patients with IBS, and the results were compared with controls. IL-4 CC genotype at position -590, IL-4 TT...
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