Article
Neuregulin genotype and medication response in Finnish patients with schizophrenia.
Neuroreport - 15 Nov 2004
Kampman Olli, Anttila Sami, Illi Ari, Saarela Marika, Rontu Riikka, Mattila Kari M, Leinonen Esa, Lehtimäki Terho
Abstract excerpt
Neuregulin 1 is involved both in neurodevelopment and neurotransmitter mechanisms in the brain. There is evidence of an association between neuregulin 1 genotype and schizophrenia. We compared neuregulin 1 genotypes in patients with schizophrenia (n=94) and control subjects (n=395) of Finnish origin by using one SNP (SNP8NRG221533) as a genetic marker. We also analyzed NRG1 genotype with regard to age at onset...
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