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Article

Mouse variants in Taf1c result in reduced survival to birth.

Developmental biology - 1 Dec 2025

Watts Jennifer L, Willeke Logan, Stottmann Rolf W

Abstract excerpt

Ribosome biogenesis is a key cellular function and disruptions in this process can lead to congenital anomalies or "ribosomopathies" with varying phenotypes including craniofacial malformations and neurodevelopment symptoms. Classically, the mouse is a robust model to understand the molecular mechanisms underlying ribosomopathies to further elucidate human pathogenesis. We identified novel compound heterozygous...

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Share to Transcription Factor TFIID
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40953792
DOI: 10.1016/j.ydbio.2025.09.011
PMCID: PMC13342686

Genes

TAF1C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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