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Article

Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish.

PloS one - 1 Jan 2014

Qin Wei, Chen Zelin, Zhang Yihan, Yan Ruibin, Yan Guanrong, Li Song, Zhong Hanbing, Lin Shuo

Abstract excerpt

Ribosome biogenesis is an important biological process for proper cellular function and development. Defects leading to improper ribosome biogenesis can cause diseases such as Diamond-Blackfan anemia and Shwachman-Bodian-Diamond syndrome. Nucleolar proteins are a large family of proteins and are involved in many cellular processes, including the regulation of ribosome biogenesis. Through a forward genetic screen...

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PMID: 24967912
DOI: 10.1371/journal.pone.0100796
PMCID: PMC4072693

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