Article
High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America - 16 Jan 2001
Buetow K H, Edmonson M, MacDonald R, Clifford R, Yip P, Kelley J, Little D P, Strausberg R, Koester H, Cantor C R, Braun A
Abstract excerpt
We describe here a system for the rapid identification, assay development, and characterization of gene-based single nucleotide polymorphisms (SNPs). This system couples informatics tools that mine candidate SNPs from public expressed sequence tag resources and automatically designs assay reagents with detection by a chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry platform....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.