Article
Direct sequence comparison of two divergent class I MHC natural killer cell receptor haplotypes.
Genes and immunity - 1 Mar 2005
Makrigiannis A P, Patel D, Goulet M-L, Dewar K, Anderson S K
Abstract excerpt
The murine Ly49 gene family encoding natural killer cell receptors for class I MHC is an example of a rapidly evolving cluster of immune response genes. Determining the genomic sequence of the 129S6/SvEvTac (129S6) Ly49 cluster and comparing it to the known sequence of the C57BL/6 (B6) region provided insight into the mechanisms of Ly49 gene evolution. 129S6 contains 20 Ly49, many of which are pseudogenes and 40%...
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