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Article

Role of CYP2C9 genetic variants for salt sensitivity and the regulation of the renin-angiotensin-aldosterone system in normotensive men.

Journal of hypertension - 1 Jan 2011

Bolbrinker Juliane, Beige Joachim, Huber Matthias, Sharma Arya M, Thomas Alexander, Deter Hans-Christian, Kreutz Reinhold

Abstract excerpt

OBJECTIVE: Cytochrome P450 (CYP) 2C9 gene polymorphisms have been implicated in regulation of the renin-angiotensin-aldosterone system (RAAS) and salt sensitivity in hypertensive patients. We tested the relevance of CYP2C9 genotypes for regulation of plasma renin activity (PRA), plasma aldosterone concentrations and blood pressure (BP) in response to changes in salt intake in normotensive individuals. METHODS:...

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PMID: 20852447
DOI: 10.1097/HJH.0b013e32833f5de5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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