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Article

Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2010

Collin Simon M, Metcalfe Chris, Refsum Helga, Lewis Sarah J, Smith George Davey, Cox Angela, Davis Michael, Marsden Gemma, Johnston Carole, Lane J Athene, Donovan Jenny L, Neal David E, Hamdy Freddie C, Smith A David, Martin Richard M

Abstract excerpt

BACKGROUND: Vitamin B(12), holo-haptocorrin, and the folate-pathway single-nucleotide polymorphisms MTR 2756A>G and SHMT1 1420C>T have been associated with an increased risk of prostate cancer. We investigated whether these and other elements of folate metabolism were associated with prostate-spe...

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Identifiers

PMID: 20852008
DOI: 10.1158/1055-9965.EPI-10-0582

Genes

SHMT1
IMPACT
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20852008-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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