Article
Polymorphisms of methylenetetrahydrofolate reductase and the risk of prostate cancer: a nested case-control study.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Feb 2006
Van Guelpen Bethany R, Wirén Sara M, Bergh Anders R J, Hallmans Göran, Stattin Pär E, Hultdin Johan
Abstract excerpt
It has been proposed that folate and polymorphisms of the enzyme methylenetetrahydrofolate reductase (MTHFR), which regulates influx of folate from DNA synthesis and repair to methylation reactions, are involved in the aetiology of cancer. To relate the MTHFR 677C-->T and 1298A-->C polymorphisms...
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