Article
Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan.
Anticancer research - 1 Sept 2010
Wu Hsi-Chin, Chang Chao-Hsiang, Tsai Ru-Yin, Lin Chih-Hsueh, Wang Rou-Fen, Tsai Chia-Wen, Chen Kuen-Bao, Yao Chun-Hsu, Chiu Chang-Fang, Bau Da-Tian, Lin Cheng-Chieh
Abstract excerpt
Prostate cancer is the most common cause of cancer death in men and is a major health problem worldwide. Methylene tetrahydrofolate reductase (MTHFR) plays an important role in folate metabolism and is also an important source of DNA methylation and DNA synthesis (nucleotide synthesis). To assess the association and interaction of genotypic polymorphisms in MTHFR and lifestyle factors with prostate cancer in...
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