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Article

MTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai.

Scientific reports - 7 Nov 2016

Wu Jun-Long, Zhou Shu-Xian, Zhao Rui, Zhang Xuan, Chang Kun, Gu Cheng-Yuan, Gan Hua-Lei, Dai Bo, Zhu Yao, Zhang Hai-Liang, Shi Guo-Hai, Qu Yuan-Yuan, Zhao Jian-Yuan, Ye Ding-Wei

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) c.677C>T and c.1298A>C variants were known to be associated with prostate cancer (PCa) risk with conflicting results, because of MTHFR and nutrient status interaction in the prostate development. In this large-scale, hospital-based, case-control study of 1817 PCa cases and 2026 cancer-free controls, we aimed to clarify the association between these two MTHFR variants...

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Source

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Identifiers

PMID: 27819322
DOI: 10.1038/srep36290
PMCID: PMC5098242

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai.PMID 27819322Read ↗

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