Article
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis.
Journal of molecular medicine (Berlin, Germany) - 1 Jul 2007
Cauchi Stéphane, El Achhab Younes, Choquet Hélène, Dina Christian, Krempler Franz, Weitgasser Raimund, Nejjari Chakib, Patsch Wolfgang, Chikri Mohamed, Meyre David, Froguel Philippe
Abstract excerpt
TCF7L2 variants have been consistently associated with type 2 diabetes (T2D) in populations of different ethnic descent. Among them, the rs7903146 T allele is probably the best proxy to evaluate the effect of this gene on T2D risk in additional ethnic groups. In the present study, we investigated the association between the TCF7L2 rs7903146 polymorphism and T2D in Moroccans (406 normoglycemic individuals and 504...
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