Article
The new type 2 diabetes gene TCF7L2.
Current opinion in clinical nutrition and metabolic care - 1 Jul 2007
Florez Jose C
Abstract excerpt
PURPOSE OF REVIEW: Common variants in the gene that encodes the transcription factor 7-like 2 (TCF7L2) have been strongly associated with type 2 diabetes. This highly reproducible association may uncover novel mechanisms of glycemic pathophysiology. RECENT FINDINGS: The initial publication of an association of common variants in TCF7L2 with type 2 diabetes in people of European descent has been followed by an...
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