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Article

Muscleblind participates in RNA toxicity of expanded CAG and CUG repeats in Caenorhabditis elegans.

Cellular and molecular life sciences : CMLS - 1 Apr 2011

Wang Li-Chun, Chen Kuan-Yu, Pan Huichin, Wu Chia-Chieh, Chen Po-Hsuan, Liao Yuan-Ting, Li Chin, Huang Min-Lang, Hsiao Kuang-Ming

Abstract excerpt

We have utilized Caenorhabditis elegans as a model to investigate the toxicity and underlying mechanism of untranslated CAG repeats in comparison to CUG repeats. Our results indicate that CAG repeats can be toxic at the RNA level in a length-dependent manner, similar to that of CUG repeats. Both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20848157
DOI: 10.1007/s00018-010-0522-4
PMCID: PMC11114631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20848157-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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