Article
Allele-specific and heritable chromatin signatures in humans.
Human molecular genetics - 15 Oct 2010
Birney Ewan, Lieb Jason D, Furey Terrence S, Crawford Gregory E, Iyer Vishwanath R
Abstract excerpt
Next-generation sequencing-based assays to detect gene regulatory elements are enabling the analysis of individual-to-individual and allele-specific variation of chromatin status and transcription factor binding in humans. Recently, a number of studies have explored this area, using lymphoblastoid cell lines. Around 10% of chromatin sites show either individual-level differences or allele-specific behavior....
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