Article
BMPR2 as a Novel Predisposition Gene for Hereditary Colorectal Polyposis.
Gastroenterology - 1 Jul 2023
Bonjoch Laia, Fernandez-Rozadilla Ceres, Alvarez-Barona Miriam, Lopez-Novo Anael, Herrera-Pariente Cristina, Amigo Jorge, Bujanda Luis, Remedios David, Dacal Andrés, Cubiella Joaquín, Balaguer Francesc, Fernández-Bañares Fernando, Carracedo Angel, Jover Rodrigo, Castellvi-Bel Sergi, Ruiz-Ponte Clara
Abstract excerpt
BACKGROUND & AIMS: Colorectal cancer (CRC) is one of the most prevalent tumors worldwide, with incidence quickly increasing (particularly in the context of early-onset cases), despite important prevention efforts, mainly in the form of population-wide screening programs. Although many cases present a clear familial component, the current list of hereditary CRC genes leaves a considerable proportion of the cases...
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