Article
Rapid differentiation of Mycobacterium tuberculosis and M. bovis by high-resolution melt curve analysis.
Journal of clinical microbiology - 1 Nov 2010
Ereqat Suheir, Bar-Gal Gila Kahila, Nasereddin Abedelmajeed, Azmi Kifaya, Qaddomi Sharif E, Greenblatt Charles L, Spigelman Mark, Abdeen Ziad
Abstract excerpt
Identification and characterization of the Mycobacterium tuberculosis strains are important for clinical and therapeutic management of tuberculosis. Real-time PCR with a high-resolution melt assay was found to improve the diagnostic process. The assay includes differentiation between M. tuberculosis and Mycobacterium bovis based on one single-nucleotide polymorphism (SNP) in the narGHJI and oxyR genes and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
