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Article

Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance.

PloS one - 7 Sept 2010

Griffin Jamie T, Cairns Matthew, Ghani Azra C, Roper Cally, Schellenberg David, Carneiro Ilona, Newman Robert D, Grobusch Martin P, Greenwood Brian, Chandramohan Daniel, Gosling Roly D

Abstract excerpt

BACKGROUND: Intermittent Preventive Treatment of malaria in infants using sulfadoxine-pyrimethamine (SP-IPTi) is recommended by WHO for implementation in settings where resistance to SP is not high. Here we examine the relationship between the protective efficacy of SP-IPTi and measures of SP resistance. METHODS AND RESULTS: We analysed the relationship between protective efficacy reported in the 7 SP-IPTi trials...

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Identifiers

PMID: 20838642
DOI: 10.1371/journal.pone.0012618
PMCID: PMC2935388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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