Article
Molecular markers of resistance to sulfadoxine-pyrimethamine during intermittent preventive treatment for malaria in Mozambican infants.
The Journal of infectious diseases - 15 Jun 2008
Mayor Alfredo, Serra-Casas Elisa, Sanz Sergi, Aponte John J, Macete Eusebio, Mandomando Inacio, Puyol Laura, Berzosa Pedro, Dobaño Carlota, Aide Pedro, Sacarlal Jahit, Benito Agustín, Alonso Pedro, Menéndez Clara
Abstract excerpt
BACKGROUND: Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a potential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to increases in resistance. METHODS: We compared the frequency of clinical episodes of malaria caused by P. falciparum...
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