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Article

Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.

The Journal of cell biology - 20 Sept 2010

Bozec Aline, Bakiri Latifa, Jimenez Maria, Schinke Thorsten, Amling Michael, Wagner Erwin F

Abstract excerpt

The activator protein-1 (AP-1) transcription factor complex, in particular the Fos proteins, is an important regulator of bone homeostasis. Fra-2 (Fosl2), a Fos-related protein of the AP-1 family, is expressed in bone cells, and newborn mice lacking Fra-2 exhibit defects in chondrocytes and osteo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20837772
DOI: 10.1083/jcb.201002111
PMCID: PMC3101588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20837772-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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