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Article

Susceptibility to the cytogenetic effects of dichloromethane is related to the glutathione S-transferase theta phenotype.

Toxicology letters - 15 Dec 2010

Olvera-Bello Alejandra E, Estrada-Muñiz Elizabet, Elizondo Guillermo, Vega Libia

Abstract excerpt

The carcinogenicity of dichloromethane (DCM) has been demonstrated by mutagenicity studies using bacteria and yeasts and using animal bioassays. Epidemiological studies indicate that exposure to DCM increases the incidences of liver and pancreas cancers. In the present study, we determine whether DCM generates DNA damage in human peripheral blood mononuclear cells (PBMCs) and whether that process depends on...

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Source

Identifiers

PMID: 20837120
DOI: 10.1016/j.toxlet.2010.09.002

Genes

GSTT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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