Article
Evaluating genotoxic risks in Brazilian public health agents occupationally exposed to pesticides: a multi-biomarker approach.
Environmental science and pollution research international - 1 Oct 2016
Franco Fernanda Craveiro, Alves Alessandro Arruda, Godoy Fernanda Ribeiro, Avelar Juliana Boaventura, Rodrigues Douglas Dantas, Pedroso Thays Millena Alves, da Cruz Aparecido Divino, Nomura Fausto, de Melo E Silva Daniela
Abstract excerpt
This is the first study demonstrating genotoxic effects and whole transcriptome analysis on community health agents (CHAs) occupationally exposed to pesticides in Central Brazil. For the transcriptome analysis, we found some genes related to Alzheimer's disease (LRP1), an insulin-like growth factor receptor (IGF2R), immunity genes (IGL family and IGJ), two genes related to inflammatory reaction (CXCL5 and CCL3),...
Topics
- Adult
- Biomarkers
- Brazil
- Comet Assay
- DNA Damage
- Genotype
- Glutathione Transferase
- Humans
- Male
- Occupational Exposure
- Pesticides
- Public Health
- Risk