Article
Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age.
Diabetologia - 1 Dec 2010
Agudo J, Martin M, Roca C, Molas M, Bura A S, Zimmer A, Bosch F, Maldonado R
Abstract excerpt
AIMS/HYPOTHESIS: The endocannabinoid system has a key role in energy storage and metabolic disorders. The endocannabinoid receptor 2 (CB2R), which was first detected in immune cells, is present in the main peripheral organs responsible for metabolic control. During obesity, CB2R is involved in th...
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