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Article

Ex3αERKO male infertility phenotype recapitulates the αERKO male phenotype.

The Journal of endocrinology - 1 Dec 2010

Goulding Eugenia H, Hewitt Sylvia C, Nakamura Noriko, Hamilton Katherine, Korach Kenneth S, Eddy Edward M

Abstract excerpt

Disruption of the Esr1 gene encoding estrogen receptor α (ERα) by insertion of a neomycin resistance gene (neo) into exon 2 (αERKO mice) was shown previously to cause infertility in male mice. While full-length ERα protein was not expressed in αERKO mice, alternative splicing resulted in the low-...

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Identifiers

PMID: 20833731
DOI: 10.1677/JOE-10-0290
PMCID: PMC2995255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20833731-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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