Article
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998
Krege J H, Hodgin J B, Couse J F, Enmark E, Warner M, Mahler J F, Sar M, Korach K S, Gustafsson J A, Smithies O
Abstract excerpt
Estrogens influence the differentiation and maintenance of reproductive tissues and affect lipid metabolism and bone remodeling. Two estrogen receptors (ERs) have been identified to date, ERalpha and ERbeta. We previously generated and studied knockout mice lacking estrogen receptor alpha and rep...
Topics
- Animals
- Estrogen Receptor alpha
- Estrogen Receptor beta
- Exons
- Female
- Genes, Reporter
- Infertility, Female
- Infertility, Male
- Male
- Mice
- Mice, Knockout
- Ovary
- Phenotype
- Receptors, Estrogen
- Recombination, Genetic