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Article

Estrogen in the male: a historical perspective†

9 Feb 2018

Abstract excerpt

Estrogens have traditionally been considered female hormones. Nevertheless, the presence of estrogen in males has been known for over 90 years. Initial studies suggested that estrogen was deleterious to male reproduction because exogenous treatments induced developmental abnormalities. However, demonstrations of estrogen synthesis in the testis and high concentrations of 17β-estradiol in rete testis fluid...

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PMID: 29438493
DOI: 10.1093/biolre/ioy043

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