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Article

Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases.

Brain : a journal of neurology - 1 Oct 2010

Clemen Christoph S, Tangavelou Karthikeyan, Strucksberg Karl-Heinz, Just Steffen, Gaertner Linda, Regus-Leidig Hanna, Stumpf Maria, Reimann Jens, Coras Roland, Morgan Reginald O, Fernandez Maria-Pilar, Hofmann Andreas, Müller Stefan, Schoser Benedikt, Hanisch Franz-Georg, Rottbauer Wolfgang, Blümcke Ingmar, von Hörsten Stephan, Eichinger Ludwig, Schröder Rolf

Abstract excerpt

Mutations of the human valosin-containing protein gene cause autosomal-dominant inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia. We identified strumpellin as a novel valosin-containing protein binding partner. Strumpellin mutations have been shown to caus...

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Identifiers

PMID: 20833645
DOI: 10.1093/brain/awq222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20833645-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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