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Article

Progressing Preemptive Genotyping of CYP2C19 Allelic Variants for Sickle Cell Disease Patients.

Genetic testing and molecular biomarkers - 1 Oct 2016

Jaja Cheedy, Barrett Nadine, Patel Niren, Lyon Matt, Xu Hongyan, Kutlar Abdullah

Abstract excerpt

AIMS: Interindividual variability in drug response and adverse effects have been described for proton pump inhibitors, anticonvulsants, selective serotonin reuptake inhibitors, tricyclic antidepressants, and anti-infectives, but little is known about the safety and efficacy of these medications in patients with sickle cell disease (SCD). We genotyped the CYP2C19 gene which has been implicated in the metabolism of...

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Share to Adolescent
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Share to Anemia, Sickle Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

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Share to Genotyping Techniques

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Source

Open in PubMed Open full text

Identifiers

PMID: 27551817
DOI: 10.1089/gtmb.2016.0001
PMCID: PMC5069730

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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