Plasma total homocysteine and the methylenetetrahydrofolate reductase 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients.

Abstract excerpt

OBJECTIVE: To evaluate the effects of plasma total homocysteine (tHcyt) and the MTHFR 677C>T polymorphism on determining the intracranial- (IC) and extracranial (EC) locations of atherosclerosis. METHODS: Brain MR angiography was performed on 463 patients with symptomatic ischaemic stroke to dete...

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