Article
The genetics of carotid dissection: meta-analysis of a MTHFR/C677T common molecular variant.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2008
McColgan Peter, Sharma Pankaj
Abstract excerpt
BACKGROUND AND PURPOSE: Carotid dissection is a recognized cause of stroke. An association has been reported between carotid dissection and elevated homocysteine levels. Homocysteine levels are partly determined by a thermolibile form of methyltetrahydrofolate reductase (MTHFR) which has a common C677T single nucleotide polymorphism (SNP). We sought to undertake a comprehensive genetic meta-analysis of this SNP...
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