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Global histone acetylation levels: Prognostic relevance in patients with renal cell carcinoma

13 Aug 2010

Abstract excerpt

Epigenetic alterations play an important role in carcinogenesis. Recent studies have suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Global histone acetylation levels (histone H3 lysine 9 acetylation [H3K9Ac], histone H3 lysine 18 acetylation [H3K18Ac], total histone H3 acetylation [H3Ac] and total histone H4 acetylation [H4Ac]) were determined in...

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Share to Epigenetics and DNA Methylation
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PMID: 20825416
DOI: 10.1111/j.1349-7006.2010.01717.x

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