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Article

Hypoacetylation of acetyl‐histone H3 (H3K9ac) as marker of poor prognosis in oral cancer

23 Mar 2017

Abstract excerpt

AIMS: Epigenetics refers to changes in cell characteristics that occur independently of modifications to the DNA sequence. Oral carcinogenesis is influenced by modifications in epigenetic mechanisms, including changes in histones, which are proteins that support chromatin remodelling for the dynamic regulation of gene expression and silencing. The dysregulation of histone acetylation can lead to the uncontrolled...

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PMID: 28326594
DOI: 10.1111/his.13218

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