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Article

Symplekin specifies mitotic fidelity by supporting microtubule dynamics.

Molecular and cellular biology - 1 Nov 2010

Cappell Kathryn M, Larson Brittany, Sciaky Noah, Whitehurst Angelique W

Abstract excerpt

Using a pangenomic loss-of-function screening strategy, we have previously identified 76 potent modulators of paclitaxel responsiveness in non-small-cell lung cancer. The top hit isolated from this screen, symplekin, is a well-established component of the mRNA polyadenylation machinery. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20823274
DOI: 10.1128/MCB.00758-10
PMCID: PMC2953045

Genes

CKAP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20823274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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