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Article

Diffusion pathways of oxygen species in the phototoxic fluorescent protein KillerRed.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 28 Oct 2010

Roy Arijit, Carpentier Philippe, Bourgeois Dominique, Field Martin

Abstract excerpt

The fluorescent protein KillerRed generates reactive oxygen species through the CALI effect. This property paves the way for the design of genetically encoded photosensitizers for use in cell killing and cancer photodynamic therapy. In this article, we have investigated the diffusion pathways of di-oxygen and the superoxide radical in KillerRed, using molecular dynamics simulations. Our results suggest that, by...

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Identifiers

PMID: 20820672
DOI: 10.1039/c0pp00141d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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