Article

All-optical spatiotemporal mapping of ROS dynamics across mitochondrial microdomains <i>in situ</i>

2023-01-07

Abstract excerpt

Hydrogen peroxide (H 2 O 2 ) functions as a second messenger to signal metabolic distress through highly compartmentalized production in mitochondria. The dynamics of ROS generation and diffusion between mitochondrial compartments and into the cytosol govern oxidative stress responses and pathology, though our understanding of these processes remains limited. Here, we couple the H 2 O 2 biosensor, HyPer7, with...

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Literature Corpus work: 3318fba8-1006-5dd9-b246-628da3ee179e
DOI: 10.1101/2023.01.07.523093

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All-optical spatiotemporal mapping of ROS dynamics across mitochondrial microdomains <i>in situ</i>DOI 10.1101/2023.01.07.523093Read

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