Article
Sodium channels as gateable non-photonic sensors for membrane-delimited reactive species.
Biochimica et biophysica acta - 1 May 2014
Ojha Navin K, Nematian-Ardestani Ehsan, Neugebauer Sophie, Borowski Benjamin, El-Hussein Ahmed, Hoshi Toshinori, Leipold Enrico, Heinemann Stefan H
Abstract excerpt
Reactive oxygen species (ROS) and reactive oxygen intermediates (ROI) play crucial roles in physiological processes. While excessive ROS damages cells, small fluctuations in ROS levels represent physiological signals important for vital functions. Despite the physiological importance of ROS, many fundamental questions remain unanswered, such as which types of ROS occur in cells, how they distribute inside cells,...
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