Article
Elimination of hepatitis B virus surface antigen and appearance of neutralizing antibodies in chronically infected patients without viral clearance.
Journal of viral hepatitis - 1 Jun 2011
Zhang Z-H, Li L, Zhao X-P, Glebe D, Bremer C M, Zhang Z-M, Tian Y-J, Wang B-J, Yang Y, Gerlich W, Roggendorf M, Li X, Lu M, Yang D-L
Abstract excerpt
Seroconversion from hepatitis B surface antigen (HBsAg) to antibodies against HBsAg (anti-HBs) usually indicates resolution of hepatitis B virus (HBV) infection. Here, two HBV-infected patients with seroconversion to anti-HBs were found to be persistently positive for HBeAg and HBV DNA. Immunohistology of liver biopsies confirmed the expression of HBV proteins in the liver of one patient. The neutralizing ability...
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