Article
Coexistence of hepatitis B surface antigen (HBsAg) and heterologous subtype-specific antibodies to HBsAg among patients with chronic hepatitis B virus infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2007
Zhang Ji-Ming, Xu Yang, Wang Xin-Yu, Yin You-Kuan, Wu Xiang-Hui, Weng Xin-Hua, Lu Mengji
Abstract excerpt
BACKGROUND: The coexistence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti-HBs) in patients with chronic hepatitis B virus (HBV) infection has been explained by the presence of viral escape mutants. Yet, no systematic analysis of such patients has been performed. We analyzed both the HBV strains and the nature of anti-HBs in such patients. METHODS: Four hundred eleven patients with chronic...
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